research programs

Carotid Artery Disease

ACT I

Multicenter randomized study evaluating the equivalence of carotid artery stenting using the Abbott Vascular Xact stent and Emboshield embolic protection system to standard endarterectomy in low-surgical-risk patients.

Post-Market Studies

To evaluate the use of FDA-approved carotid stents and embolic protection systems CHOICD (Abbott), SAPPHIRE WW (Cordis), and CREATE PAS (ev3) in high-surgical-risk patients.

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Renal Artery Disease

VIVA III: FORTRESS

A non-randomized study to evaluate the safety and filter efficiency of the Lumen Biomedical FiberNet Embolic Protection System when used in conjunction with the FDA-approved Express SD stent system (Boston Scientific) for stenting of ostial atherosclerotic renal lesions.

HERCULES

A non-randomized study to assess the safety and efficacy of the RX Herculink Elite Renal Stent System (Abbott) for the treatment of suboptimal post-procedural percutaneous transluminam angioplasty (PTA) in atherosclerotic de novo or restenotic renal artery stenosis in patients with uncontrolled hypertension.

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Lower-Extremity Peripheral Vascular Disease

VIVA I: XCELL

A non-randomized study to evaluate the safety and performance of the Expert stent (Abbott) in below-the-knee lesions as part of an overall treatment for infrapopliteal lesions in patients undergoing percutaneous intervention for critical limb ischemia.

VIVA II: SALVAGE

A non-randomized study to evaluate the safety and performance of Spectranetics LASER used with Viabahn Endoprosthesis with Heparin Bioactive Surface (Gore) for the treatment of superficial femoral artery in-stent restenosis.

iCAST

A non-randomized study to evaluate the non-inferiority of the iCAST covered stent (Atrium Medical) for the treatment of iliac artery stenoses in patients with de novo or restenotic lesions in the common and/or external iliac arteries.

DURABILITY

A non-randomized study to evaluate the use of the PROTEGE EverFlex Nitinol stent system (ev3) in lesions of the superficial femoral artery and proximal popliteal artery.

ZILVER PTX

A randomized study to compare the long-term safety and effectiveness of the Zilver PTX Drug-Eluting Vascular Stent (Cook Medical) to percutaneous transluminal angioplasty control in patients with de novo or restenotic lesions of the above-the-knee femoropopliteal artery that have not been previously stented.

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We offer numerous clinical research studies for the treatment of your cardiovascular disease and related problems:

Carotid Artery Disease

Abdominal Aortic Aneurysm

Renal Artery Disease

Lower-Extremity Peripheral Vascular Disease

Device-Based Therapy for Congestive Heart Failure

Device-Based Management of Arrhythmia

Device-Based Therapy for Congestive Heart Failure

Promote Q CRT-D and Quartet LV Lead

A multi-center non-randomized study to assess the safety and efficacy of the new multi-polar left ventricular (LV) lead (St. Jude Medical) in the performance of cardiac resynchronization therapy defibrillator (CRT-D) in patients with impaired left ventricular systolic function and congestive heart failure

OPTIMIZE CRTD

A multi-center randomized study to assess the safety and efficacy of the automated optimization of pacing timing using the QuickOpt (St. Jude Medical) algorithm as compared to other methods.

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